Use Alt + A on Windows or Linux and Command + Shift + A on Mac in a Zoom desktop meeting. Zoom Phone has separate call shortcuts; use the meeting keys for meetings. The web app lists enabled spacebar temporary unmute, not these desktop toggle keys.
In desktop Settings → Keyboard shortcuts, inspect or change an assignment. On Windows and Mac, supported shortcuts can be made global using the checkbox beside them. Confirm that option for the action you want to use while another app is active. Zoom keyboard settings.
For push to talk, enable the spacebar temporary-unmute option in Settings → Audio. Start muted, bring the Zoom meeting window into focus, and hold Space while speaking. Host restrictions still apply. Zoom push-to-talk setup.